Erosions of Psoriatic Plaques Due to Methotrexate
نویسندگان
چکیده
منابع مشابه
Low-dose methotrexate-induced ulcerated psoriatic plaques: A rare case.
INTRODUCTION Low-dose methotrexate is an effective and safe management for extensive and severe psoriasis. It may cause adverse reactions ranging from trivial to life threatening. Among them, hepatotoxicity and pancytopenia are the common serious side effects, whereas painful ulceration of psoriatic plaques as an early cutaneous manifestation of low-dose methotrexate toxicity has rarely been re...
متن کاملConjunctivitis, mucosal erosions, and moist cutaneous plaques
Departments of Dermatology and Pathology and tory Medicine, Perelman School of Medicine at the ity of Pennsylvania and the Department of Medicine, of Dermatology, Pritzker School of Medicine at the ity of Chicago. ources: None. f interest: None declared. dence to: Caroline A. Nelson, MD, 3600 Spruce Street, 2 y Building, Philadelphia, PA 19104. E-mail: Caroline. @uphs.upenn.edu. JAAD Case Repor...
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Methotrexate (MTX) is a folic acid analogue with antiproliferative and antiinflammatory effects. In the past several years, MTX has become the most commonly used agent in patients with severe, destructive psoriatic arthritis (PsA), with positive clinical results. Liver changes and serum enzyme level increases do not seem to be a major problem in PSA patients treated with MTX. In addition, PSA p...
متن کاملPsoriatic plaques exhibit red autofluorescence that is due to protoporphyrin IX.
In evaluating the autofluorescence properties of normal and diseased skin we discovered that psoriatic plaques can emit a distinct red fluorescence when illuminated with UVA or blue light. Using a macrospectrofluorometer equipped with a 442 nm excitation laser, a sharp in vivo fluorescence emission peak around 635 nm could be demonstrated within the plaques of 34 of 75 (45%) patients with psori...
متن کاملMethotrexate induced mucosal erosions and ulcerations
The patient reported that his mouth and throat were painful and he had difficulty in swallowing food. Initially, the ulcers had persisted over the two weeks following the prescription of Dynexan®, Augmentin 1g BDS for 5 days, Andolex C® and Mucain mouthwash®, by his general practitioner. Subsequent referral to an ENT surgeon had resulted in confirmation of an extra-oesophageal reflux component....
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ژورنال
عنوان ژورنال: Acta Médica Portuguesa
سال: 2021
ISSN: 1646-0758,0870-399X
DOI: 10.20344/amp.12992